YMMV revisited

Some time ago, I wrote about "YMMV," or "your mileage may vary," the concept that sometimes what works well for one person doesn't work for another. The diabetes community was aware of that variation, but the evidence was annectotal and no one had studied it formally until a study in an Israeli cohort.

Now someone has done a similar study in mostly midwestern Americans without diabetes. The results are similar. Look at Figure 2A to see how people's blood glucose can vary after the same meal, in this case a bagel with cream cheese. One person's glucose levels went up to 190 and another to only 110. Note that these are people who haven't been diagnosed with diabetes. Whether they're on their way to diabetes is not known.

The researchers took 72 parameters into account in developing their model, which is designed to predict  how someone will react to a particular meal. You'll have to go to the Supplemental Content section to see these parameters, which I won't try to list here. They include species of 23 bacteria in the microbiome as well as usual things like nutrients, BMI, age, and CGM results.

The model is not yet available to the general public.