Saturday, March 27, 2021

Fructose and Triglycerides

 When I was diagnosed with type 2 diabetes in 1996, it was thought that although fructose, which is half of sucrose (table sugar; the other half is glucose), didn't raise blood glucose (BG) as much as glucose, it could have an effect on triglycerides (fats).

One source said that although fructose didn't affect blood triglycerides in people with unimpaired glucose tolerance, it could raise them in people with defects in carbohydrate metabolism (e.g., people with diabetes) even at relatively low levels of fructose intake.

Yet despite this, products sweetened with fructose were sold as diabetes friendly. We have to remember that factors other than BG levels are important for health, so higher triglycerides are not benign.

A recent study shows that consumption of fructose or sucrose, but not glucose, doubles the synthesis of triglycerides in the liver. The full text can be found here. Note that this study was done on "healthy lean men." Results might be even more pronounced in those with diabetes.

Increased fat production in the liver is a significant first step in the development of common diseases such as fatty liver and type-2 diabetes, so this is important.

Some people say that diabetes isn't caused by eating sugar. Are they wrong?



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